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Manzolam (Alprazolam)

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Manzolam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Manzolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Manzolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpose, Alpradol, Alpram, Alpronit, Alprowon, Alzam, Alzex, Alzolite, Alzot, Alzotime, Anquil, Anxigon, Anxyl, Axizox, Depser, Destres, Diprex, Ecsit, Enxolam, Fluxin, Fultop, Jolistar, Nokzok, Omelam, Prozolam, Rivcam, Samrox, Serxanti, Sinzolam, Somaspas, Somnirest, Tancalm, Tenolam, Tenscure, Tensfree, Texidep, Trika, Visram, Xylonite, Zenax, Zolran, Zoltweet, Zotin

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Manzolam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Manzolam XR may be habit-forming and should be used only by the person it was prescribed for. Manzolam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Manzolam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Manzolam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Manzolam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Manzolam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Manzolam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Manzolam XR dosage information


If you have been prescribed Manzolam for medical reasons, the best way to avoid a Manzolam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Manzolam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Manzolam XR dosage information

Side effects

The most common side effects associated with Manzolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Intelligence measures and stage 2 sleep in typically-developing and autistic children. In recent years it has been shown that a decrease in plasma fibrinolytic activity is associated with increased risk of thrombosis. Change in Functional Arm Use Is Associated With Somatosensory Skills After Sensory Retraining Poststroke. The proposed method is robust, accurate,and sensitive and may be used with confidence in Phase II MS trials. We retrospectively picked up patients who had been prescribed sitagliptin for 6 months during the continuous prescription of oral glucocorticoids between October 2010 and October 2013 by a chart-based analysis, and compared the data before the sitagliptin treatment with the data at 6 months after the sitagliptin treatment started. The working mechanisms of 3 classical restricted Bayesian classifiers, namely, NB, TAN and KDB, were analysed and summarised. We report three pediatric patients with pulmonary hypertension and raised pulmonary resistance, including two infants, in whom heterotopic transplantation was performed with smaller donor hearts. We evaluated the association between exposure to arsenic, measured in toenails, and blood DNA methylation in Alu and Long Interspersed Nucleotide Element-1 (LINE-1) repetitive elements in elderly men environmentally exposed to low levels of arsenic. Receiver operator characteristic analysis was used to compare the power to identify responders between the albenza end of the first and the end of the second cycle of NCT. Pacific people are at a significantly higher risk of experiencing a TBI than NZ Europeans and targeted prevention efforts are needed.

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