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Tindamax (Tinidazole)
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Tindamax

Tindamax is an antibiotic, which belongs to a group of medicines called nitroimidazoles. Tindamax works by killing or stopping the growth of bacteria causing your infection. Tindamax will not work against viral infections such as colds or flu.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

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Tofranil, Furadantin, Omnicef, Colcrys, Elocon, Brutiz, Celecap, Calday, Chronol, Corbetazine, Amirone, Dorolid, Alpam, Xalacom, Renacardon,

Also known as: Tinidazole

Description

Tindamax manufacturer is Pfizer. Tindamax tablets contain active ingredient is Tinidazole, a 5-nitroimidazole anti-parasitic agent, which belongs to a drug class Amebicides, Antimalarials and gynecological Antiinfectives.

Dosage

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Take Fasigyn with a glass of water during or after a meal. Swallow the tablets whole. It is best to take the medicine at the same time each day.

For bacterial infections, this medicine is not recommended for use in children less than 12 years as it has not been tested in this age group.

For protozoal infections, Fasigyn 500mg film-coated tablets can be used in children and has not been shown to cause any different side effects or more problems than it does in adults.

The dose and length of treatment depends upon the infection being treated. If you are on dialysis, your doctor may prescribe a different dose.

The doses most commonly used for the different infections are shown in the table below:

For treating the infection associated with stomach ulcers. The usual dose is 1 tablet (500mg) taken twice a day. Your doctor will probably prescribe two other medicines to be taken with Fasigyn 500mg film-coated tablets. Treatment with the three medicines together will usually be for 1 week.

For treating most bacterial infections. The usual dose is 4 tablets (2g) on the first day then 2 tablets (1g) once a day or 1 tablet (500mg) twice a day. The usual length of treatment is 5 to 6 days.

For treating bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection). The usual dose is 4 tablets (2g) given as a single dose. For vaginitis you may be given 4 tablets (2g) on two consecutive days.

For preventing bacterial infections after surgery. Usually 4 tablets (2g) are given as a single dose about 12 hours before surgery.

For treating protozoal infections. For treating intestinal amoebiasis (a stomach infection). Adult: The usual dose is 4 tablets (2g) once a day for 2 to 3 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 3 days.

For treating amoebic involvement of the liver (a liver infection). Adult: The usual dose is 3 to 4 tablets (1.5 to 2g) once a day for 3 to 6 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 5 days.

For treating giardiasis (an abdominal infection) and trichomoniasis (an infection of the sex organs in males and females). Adult: The usual dose is 4 tablets (2g) given as a single dose. Child: The usual dose is 50 to-75mg/kg of body weight given as a single dose.

Your doctor will calculate the dose required for a child and may repeat the dose once if the infection has not cleared up completely.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Keep Fasigyn in its original packaging until it is time to use it. If you take Fasigyn out of its packaging, it may not keep as well.

Keep your Fasigyn in a cool, dry place where it stays below 25 degrees C.

Do not store Fasigyn or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill. Heat and dampness can destroy some medicines.

Keep your Fasigyn where young children cannot reach it. A locked cupboard at least one and a half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Tindamax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Tindamax if you are allergic to Tinidazole, to any antibiotic from the class Amebicides. Do not take Tindamax if you are allergic to any of the other ingredients comprised in Tindamax. Do not take Tindamax if you have a history of severe allergic reactions associated with using antibiotics. Do not take Tindamax you have a blood disorder or a history of blood disorders. Do not take Tindamax if you have any disease of the brain, spinal cord or nerves. Do not take Tindamax you have central nervous system (CNS) disease, including epilepsy. Do not take Tindamax you are in the first 13 weeks of pregnancy, planning to have a baby, or you are breastfeeding. Do not drive or operate machinery if you feel dizzy or numb after taking Tindamax. Do not consume alcohol while you are taking Tindamax and for 3 days afterwards. Alcohol may cause an upset stomach, vomiting, stomach cramps, headaches, sweating, and flushing (redness of the face).

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Measuring the anticoagulant effect of low molecular weight heparins in the critically ill. High concentrations of both antagonists directly modulated H2O2 release and retained the strain-related differences seen with Met-ENK. Flow cytometric analysis of anti-platelet antibodies in patients with chronic idiopathic thrombocytopenic purpura (ITP) using acid-treated, formalin-fixed platelets. The value of clinical application of Collapat appears to be doubtful. The antimicrobial activities of non-nanoformulated apo (iron free), Fe-bLf and native forms of Australian bLf against pathogenic Salmonella typhimurium (wild strain) were studied in vitro. Prevalence peaks in breast cancer incidence depended on the age groups covered by the screening, the length of the implementation of screening, and the extent of background opportunistic screening. All the members were offered the possibility of forming a part of the study. Gene and protein expression analysis of brown and white adipose tissues (WATs) were performed.

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Differentiation of human oligodendrocytes from pluripotent stem cells. It was reported that pediatric patients, born small for gestational age or with idiopathic short stature who were homozygous or heterozygous for this variant responded better to GH treatment than those homozygous for the full-length allele (fl-GHR). When the C3H mice were treated with anti-CD4 mAb, 1 x 10(8) s.c. Disseminated posttraumatic mucocele of all the paranasal sinuses. Despite presenting similar degrees of immunosuppression, not all individuals at-risk ultimately develop fungal diseases. Tamoxifen flare--an unusual case of hypercalcaemia and transient rapidly progressive pancytopenia. The anti-cancer actions of O6-methylguanine-DNA-methyltransferase in relation to colon polyps.

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Semitendinosus, longissimus dorsi, and gastrocnemius muscles were removed from 4 sets of 2-day-old splayleg piglets, each with a corresponding normal litter mate. We provide here a rationale to include all types of sRNAs in sRNA sequencing analyses, which will aid in the discovery of their biological functions and physiological relevance. Rethinking what is important: biologic versus social predictors of childhood health and educational outcomes. An ammonium chloride loading test revealed a defect in acid excretion and led to the diagnosis of incomplete renal tubular acidosis. We describe a patient who developed neuropathic cancer pain unresponsive to opioid escalation and spinal administration of a combination of bupivacaine-morphine and was subsequently treated by subcutaneous continuous ketamine infusion. The aim of the study was to assess the profile of autonomic dysfunction in patient with primary brain tumors, with attempt to estimate the additional factors in pathogenesis of dysautonomia. Flow and composition of leg lymph in normal men during venous stasis, muscular activity and local hyperthermia. In order to challenge this assessment, we analyze how and how much the genetic variations located in the gene that codes for HTR1B impacts on the psychiatric phenotypes by reviewing the literature on this topic. Normative data for BESS scores and modified BESS scores were created in a cohort of healthy children.

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Leupeptin inhibits hydrolysis of the substrate carbobenzoxy-Leu-Leu-Arg-2-naphthylamide, but not hydrolysis of carbobenzoxy-Gly-Gly-Leu-p-nitroanilide or carbobenzoxy-Leu-Leu-Glu-2-naphthylamide, demonstrating the presence of the third activity. The crystals was produced by mixing CaCl2 and KH2PO4 with or without GA (4g/L) at room temperature for 3, 12, 24h and 3, 7, 14 days. We demonstrated that tolvaptan had similar effects on cardiac and renal function and led to a similar prognosis in the long term, compared to carperitide. However, NnaPLA2 and notexin did not markedly disrupt the integrity of cellular membrane as evidenced by membrane permeability of propidium iodide. Activation of locus coeruleus (LC) produced short- and long-term potentiation of the perforant path-evoked potential on both pipettes. Colour Doppler sonography is a noninvasive technique that can replace pelvic arteriography in the assessment of patients with trophoblastic diseases.

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A prospective study of successful long-term adjustment in alcohol dependence: social drinking versus abstinence. Radiographs and scoliotic curve data were also obtained for the experimental group. Toward pharmacologic modification of joint damage in osteoarthritis. We show that ITP purification yields genomic DNA samples which can be quantitated with fluorescence measurements and are immediately compatible with polymerase chain reaction (PCR) (e.g., a PCR-friendly solution free of significant inhibitors). Recently, attention has been directed toward elevating MAP by establishing auto-PEEP when ventilating with an inverse inspiratory to expiratory ratio in opposition to applied PEEP. The model proposed here assumes that the driving force taking the molecules out from the nanoparticle surface into the bulk solvent is the gradient of osmotic pressure. Nicotine increased NGF expression both at the mRNA and protein level and also created a receptor imbalance deriving from increased expression of the pro-inflammatory p75(NTR) receptor without any concomitant change in the high-affinity trkA receptor. The amount of APTES incorporated in the silica framework increased with the APTES concentration in the synthesis gel, while the ordering of the mesoporous structure gradually decreased. Three groups of eight elderly volunteers received 400 or 800 mg netivudine or placebo once daily for 8 days. It also decreased AAP-induced liver injury, accompanied by decreased expression of pJNK, Bax and tBid in the liver.

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Hippuryl-L-histidyl-L-leucine (Hip-His-Leu) is used as substrate and the released hippuric acid is measured. The hyaluronan concentrations were high in penile tissue and urinary bladder, while testis, epididymis and the ductus deferens contained only little hyaluronan. Endoscopic minor papilla sphincterotomy is most effective in the treatment of patients with PD and pancreatic stones. This study tested if nicotine reproduces motor effects of smoking and assessed the role of slow wave disruption in inducing hypomotility and the prostaglandin dependence of dysrhythmic responses. Often, pharmacological treatment of the hyperglycaemia is necessary, in which case sulphonylureas, metformin, alpha-glucosidase inhibitors such as acarbose, or insulin may be employed. Reaction mechanism of the mandelate anion racemization catalyzed by mandelate racemase enzyme: a QM/MM molecular dynamics free energy study. In female musk shrews, the first mating initiates the onset of puberty. We identify two sites of phosphorylation as tyrosine residues 31 and 118, each of which conforms to the Crk SH2 domain binding motif, (P)YXXP. Logistical barriers to career development in academic cardiovascular multimodality imaging-challenges for future mentors. This results in a larger corolla tube mouth in thrum flowers and represents a new and previously undocumented heteromorphic variation between pin and thrum flowers.

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Differences in resistant starch content were found between the two maize tortillas, which might be related to the softer texture of blue-maize tortilla. To determine whether RPA and POT1 also modulate WRN branch migration activity, we examined biologically relevant mobile D-loops that mimic structures in HR strand invasion and at telomere ends. To determine whether pupil stretch during phacoemulsification affects postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), and inflammation compared with results in patients without pupil stretch. There is an increasing understanding that Natural Killer (NK) cells not only exhibit direct activity against bacteria, but also exert indirect antibacterial activity through interaction with other immune cells via cytokines and interferons. Naked cuticle (Nkd) is a novel and evolutionarily conserved inducible antagonist of Wnt/beta-catenin signaling that is crucial for segmentation in the model genetic organism, the fruit fly Drosophila melanogaster. An anaesthetic technique for unpremedicated patients undergoing minor surgery is described.

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Complete resolution of interstitial pregnancy in both instances with two subsequent, successful intrauterine pregnancies delivered at term in the second patient. In addition, evaluation of toxicities of halogen-substituted short-chain carboxylic alcohols indicated that their mechanisms vary, depending upon the type of substitution and the system. Little research has considered those sources of stress likely to enhance well-being and, by implication, learning. A protocol to optimize the duration of antimicrobial therapy (DAT) for uncomplicated pneumonia at hospital discharge was evaluated. Knee pain in children and adolescents is one of the most prevalent complaints in a pediatric practice, accounting for at least a third of musculoskeletal complaints. The combination of these two constraints suggests a theoretically derived interpretation for many anatomical and physiological features and predicts several others. Nonetheless, ostriches, like humans, exhibit a gait-transition hysteresis that is not explained by steady-state locomotor dynamics and energetics. In addition, when emotional changes were reported after electrical stimulation, SCR amplitude for the positively valenced emotions was larger than for the negative ones. And this could offer a logical approach for the use of substances with a multi-target action, e.g.

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A retrospective comparison of magnetic resonance imaging (MRI) and quantitative electromyography (EMG) findings in patients with compressive cervical myelopathy (CCM). In addition, these morphological models highlight that the relationship between BV/TV and BS/TV is not linear at high BV/TV as suggested in the literature but is closer to a square root function. Stratifying the results according to hemorrhagic activity, electrocoagulation should be clearly effective in those patients with spurting hemorrhage, taking into account several limitations: deep ulcers bearing gross vessels, and lack of cooperation by the patient. Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL. Impedance plethysmography was used to measure bilateral blood flow in the forearms, hands, and digits of seven healthy male subjects. This observation is further reinforced by demonstrating the direct interaction of DegU on amyE promoter.

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TH-302 may therefore be an attractive therapeutic agent with strong activity as a single agent and in combination with chemotherapy against OS. The C terminus encodes an acidic domain with a net negative charge of -10 and the ability to mediate transcriptional activation. Optimal conditions for its mild photolyti removal were established. Modification of cardiovascular response and histamine release by prophylactic antibiotic drugs in complicated surgery: a prospective randomized trial in a pig experimental model. Cancer in ataxia-telangiectasia patients: analysis of factors leading to radiation--induced and spontaneous tumors. However, clinicians focus on the drug formulation and a relatively little effort was made in improving the design of aerosol devices and individualizing inhalation therapy in acute and critically ill patients.

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Since c-fos and c-jun have been shown to play a role in apoptosis in other cell types, the ability of insulin to regulate expression of these genes may be central to its ability to act as a survival factor for lens epithelial cells. Milrinone has been proposed as an effective treatment for pulmonary hypertension (PH) and right ventricular (RV) dysfunction. Since bilateral nephrectomy will always provoke severe anemia, it should be reserved to special cases of severe hypertension. There was a significant rank correlation between the prometrium gel transformity of elements and that of trophic levels. Here, we review currently available evidence focusing on medical conditions that may affect the patient-provider decision-making process regarding the use of radiation therapy. Such observations could not be explained by increased caloric consumption since male and female RGS9 KO mice demonstrated equivalent daily food intake as compared to their respective WT littermates. The R/T ratio method is used to extract the anisotropic complex refractive indices of a polyimide film with known uniaxial symmetry. O6-methylguanine-DNA methyltransferase in human brain tumors detected by activity assay and monoclonal antibodies. Relationship between exercise heart rate and age in men vs women.

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Predictors of root canal treatment in teeth with full coverage restorations. We surveyed 8749 doctors within a defined region (eastern Denmark) via a single-issue, mailed questionnaire. Impact of Neuroradiology-Based Peer Review on Head and Neck Radiotherapy Target Delineation. The Treg/Th17 balance was disturbed by uraemia, especially in patients with adverse cardiovascular events. The role of white-coat hypertension (WCH) and the white-coat-effect (WCE) in development of cardiovascular disease (CVD) risk remains poorly understood. Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs-A Review.

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On exploration, three cavities were found within the liver containing necrotic material. Bone marrow diagnosis in lymphoproliferative disorders: comparison of results obtained from conventional histomorphology and immunohistology. SlyA, a regulatory protein from Salmonella typhimurium, induces a haemolytic and pore-forming protein in Escherichia coli. These findings provide the basis for using luminescence to measure ATP concentration continuously in in vitro biological systems such as isolated mitochondria. However, the potential clinical implications of LAPTM4B-35 in HCC are still unclear. Immunohistochemistry revealed that large, pale epithelial cells expressed immunophenotypes similar to those of luminal cells in the transitional portions between the secretory portions and the coiled ducts. The lack of simple objective tests for evaluating the hand-arm vibration syndrome makes it difficult to, eg, confirm crestor 10 mg tablet uses the history of its different components objectively and estimate the extent of the disability it causes. Anti-NGF antibody was used to investigate how it affected the protein expression of pan-Ras, pERK and c-fos in the dorsal root ganglion and the lung of the asthma group.

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Mean elimination half-lives of the drug were 3.20 hours in 2 patients under 7 days of age and 2.31 hours in 5 patients from 7 days of age or older. Semiconductor nanocrystals: structure, properties, and band gap engineering. Our objectives were to investigate whether COMT expression, by the virtue of 2ME formation, affects the growth of huLM, and to explore the cellular and molecular mechanisms whereby COMT expression or treatment with 2ME affect these cells. Dual function of PilS during transcriptional activation of the Pseudomonas aeruginosa pilin subunit gene. The results are contrasted with the lectin induced agglutination of other parasite species and mammalian cells. Capromorelin at the doses tested was safe and well tolerated in both SCI and able-bodied participants and also showed similar pharmacokinetics with dose-dependent increases in concentration and drug exposure. Time course of the corticosteroid-dopaminergic interaction during metyrapone and dexamethasone administration. Urgent percutaneous nephrolithotomy for acute kidney injury secondary to bilateral stones: is it safe and effective in infants?.

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